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------=_NextPart_01C9C745.68FB4BA0 Content-Location: file:///C:/20C8DEAF/slides-intro_files/master03.xml Content-Transfer-Encoding: quoted-printable Content-Type: text/xml; charset="utf-8" ------=_NextPart_01C9C745.68FB4BA0 Content-Location: file:///C:/20C8DEAF/slides-intro_files/preview.wmf Content-Transfer-Encoding: base64 Content-Type: image/x-wmf AQAJAAADjGQAAAAAcWQAAAAABQAAAAsCAAAAAAUAAAAMAoACwAMFAAAABwEDAAAAcWQAAEELIADM AGsAoAAAAAAAgALAAwAAAAAoAAAAoAAAAGsAAAABABgAAAAAAKDIAAAAAAAAAAAAAAAAAAAAAAAA YwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAA awAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAA YwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAA awAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAA YwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAA awAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAA 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Second level
Third level
Fourth level
Fifth level
test
Overview
‹#›
------=_NextPart_01C9C745.68FB4BA0 Content-Location: file:///C:/20C8DEAF/slides-intro_files/master18.xml Content-Transfer-Encoding: quoted-printable Content-Type: text/xml; charset="utf-8" ------=_NextPart_01C9C745.68FB4BA0 Content-Location: file:///C:/20C8DEAF/slides-intro_files/pres.xml Content-Transfer-Encoding: quoted-printable Content-Type: text/xml; charset="utf-8" ------=_NextPart_01C9C745.68FB4BA0 Content-Location: file:///C:/20C8DEAF/slides-intro_files/slide0002.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" SABS I: Vascular Physiology
SABS I: Vascular Physiology
Steven J. Miller, Ph.D. =
Office: 274-2657
E-Mail: sjmiller@= iupui.edu
http://www.iuvascular.com/U= nthank/teach.html
INTRODUCTION
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SABS I
Overview
2
A. Primary Function of the Peripheral Circulation
•Maintain tissue environme= nt for optimal cell survival and function (HOMEOSTASIS)
•Homeostasis requires:
= •Exchange
= •Transportation
= •Maintenance of internal temperature and pH
•Defense against foreign agents  
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SABS I
Overview
3
Transportation and Exchan= ge
•To tissues:  O2, metabolic fuels, hormones
R= 26; 
•From tissues: CO2, met= abolic wastes, hormones
R= 26; <= /u>
•   As tissue needs cha= nge, how are
transportation and exchange altered?
R= 26; =
•
Fuels include glucose, amino acids, fatty acids.  Wastes include urea.
------=_NextPart_01C9C745.68FB4BA0 Content-Location: file:///C:/20C8DEAF/slides-intro_files/slide0006.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" SABS I: Vascular Physiology
SABS I
Overview
4
B. Major Components of the Peripheral Circulation=
•1.  Blood= 3;
<= span style=3D'font-size:86%'>•Plasma: carriers, coagulation, water balance, pH••Red blood cells: transportation of O2, CO2®bicarbonate, pH
•
<= span style=3D'font-size:86%'>•White blood cells: immune function
•• Platelets: hemostasis (procoagulan= ts, vasoconstrictors, aggregation), growth factors
<= span style=3D'font-family:"CG Times";font-size:86%;visibility:hidden'>•
<= span style=3D'font-size:86%;visibility:hidden'>•
=
<= ![if !vml]>=3D13-1
This is a test
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SABS I
Overview
5
B. Major Components of the Peripheral Circulation
R= 26;2.  Vessels
R= 26;
•Conduit arteries<= /u>: elastic vessels, pressure reservoir, low resistance, distribute blood to organs =
•Resistance arteries: (<= span style=3D'font-family:Symbol;mso-bidi-font-family:"Times New Roman";font-si= ze: 88%;color:white;mso-color-index:3;mso-char-type:symbol'>³100µm diameter),=   at least 2 continuous layers of innervat= ed vascular smooth muscle.
• Arterioles:  (5-100+ µm diameter),  single layer of <= /span>innervated vascular smooth muscle.
•
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------=_NextPart_01C9C745.68FB4BA0 Content-Location: file:///C:/20C8DEAF/slides-intro_files/slide0007.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" SABS I: Vascular Physiology
SABS I
Overview
6
B. Major Components of the Peripheral Circulation
R= 26;2.  Vessels
•Capillaries: (5-10µm) single layer of endothelial cells=
•Venules<= /u>: single laye= r of innervated vascular smooth muscle; larger venules paired with compan= ion arterioles
• Veins: conduits for the return of blood to the heart, contain innervated smooth muscle cells and provide a volume rese= rvoir
•
------=_NextPart_01C9C745.68FB4BA0 Content-Location: file:///C:/20C8DEAF/slides-intro_files/slide0008.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" SABS I: Vascular Physiology
SABS I
Overview
7
B. Major Components of the Peripheral Circulation
R= 26;2.  Vessels = ;
•Macrocirculation: vessels = responsible for the blood distribution to, or collection from, tissues.
•Microcirculation: vessels embedded within tissues and responsible for the perfu= sion of the tissues.
R= 26; =
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