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------=_NextPart_01C9C746.4F775AB0 Content-Location: file:///C:/DE4AB113/slides-capillaries_files/master03.xml Content-Transfer-Encoding: quoted-printable Content-Type: text/xml; charset="utf-8" ------=_NextPart_01C9C746.4F775AB0 Content-Location: file:///C:/DE4AB113/slides-capillaries_files/preview.wmf Content-Transfer-Encoding: base64 Content-Type: image/x-wmf AQAJAAADjGQAAAAAcWQAAAAABQAAAAsCAAAAAAUAAAAMAoACwAMFAAAABwEDAAAAcWQAAEELIADM AGsAoAAAAAAAgALAAwAAAAAoAAAAoAAAAGsAAAABABgAAAAAAKDIAAAAAAAAAAAAAAAAAAAAAAAA YwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAA awAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAA YwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAA awAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAA YwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAA awAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAAYwAAawAA 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------=_NextPart_01C9C746.4F775AB0 Content-Location: file:///C:/DE4AB113/slides-capillaries_files/master18.xml Content-Transfer-Encoding: quoted-printable Content-Type: text/xml; charset="utf-8" ------=_NextPart_01C9C746.4F775AB0 Content-Location: file:///C:/DE4AB113/slides-capillaries_files/pres.xml Content-Transfer-Encoding: quoted-printable Content-Type: text/xml; charset="utf-8" ------=_NextPart_01C9C746.4F775AB0 Content-Location: file:///C:/DE4AB113/slides-capillaries_files/slide0097.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" SABS I: Vascular Physiology
SABS I: Vascular Physiology
Steven J. Miller, Ph.D. =
Office: 274-2657
E-Mail: sjmiller@iupui.edu =
http://www.iuvascular.com/U= nthank/teach.html
CAPILLARIES
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SABS I
Capillaries
2
III. Capillaries
A.<= span style=3D'mso-bidi-font-family:"Times New Roman";font-size:88%'>Fundamental Facts
1.Transcapillary exchange is essential for = cell function and survival.
2.Normal tissue function requires selective permeability of capillaries to different solutes.
3.The permeability of capillaries in various tissues must be different for normal organ function to occur.
4.Net water movement across capillary must = be controlled = to maintain proper tissue hydration
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SABS I
Capillaries
3
III. Capillaries
<= span style=3D'font-size:114%'>B.<= span style=3D'mso-bidi-font-family:"Times New Roman";font-size:114%'>Transcapil= lary Exchange of Solute
<= span style=3D'mso-special-format:bullet;color:#99CCFF;mso-color-index:5;positio= n: absolute;left:-8.86%;top:-.08em;font-size:110%'>•Mechanisms for exchange&#= 13;
<= span style=3D'mso-special-format:bullet;color:yellow;position:absolute;left:-8.= 21%; top:-.08em;font-size:110%'>•Diffusion
<= span style=3D'mso-special-format:bullet;color:yellow;position:absolute;left:-8.= 21%; top:-.08em;font-size:110%'>•Bulk flow
<= span style=3D'mso-special-format:bullet;color:yellow;position:absolute;left:-8.= 21%; top:-.08em;font-size:110%'>•Pinocytosis/vesicular transport
<= ![if !vml]>=3D19-15
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SABS I
Capillaries
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III. Capillaries
<= span style=3D'font-size:114%'>B.<= span style=3D'mso-bidi-font-family:"Times New Roman";font-size:114%'>Transcapil= lary Exchange of Solute
•Factors contributing to rapid diffusiona= l exchange&#= 13;
•Diffusion distance – cells within 20 mm of a capillary&= #13;
<= span style=3D'font-size:117%'>•Large total surface area – 7000 sq. ft.
•Slow rate = of blood flow – 0.1 to 1.0 mm/sec (vs. 40 cm/sec = in aorta
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SABS I
Capillaries
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III. Capillaries
B.Transcapillary Exchange of Solute
•Diffusion&#= 13;
•for a single capillary: Js=3D[PS(Co-Ci)]/d
•Js =3D solute transfer= red, moles/min
•d =3D distance for diffusion
•(Co-Ci) =3D concentrat= ion gradient from outside to inside of capillary
•<= /span>PS =3D permeability coefficient
–P =3D c= apillary permeability of specific substance
–S =3D c= apillary surface area
•&#= 13;
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Difference in PS for various solutes due primarily to pathway available for exchange
<= span style=3D'font-weight:bold;visibility:hidden'>B. =
<= span style=3D'visibility:hidden'>•
Substance
Molecular Weight
Molecular Radius (Å)
Specific = Permeability
H2O
18
1.5
28
NaCl
58
2.3
15
Urea
60
2.6
14
Glucose
180
3.7
6
Sucrose
342
4.8
4
Inulin
5,500
12-15
0.3
Myoglobin
17,000
19
0.1
Serum Albumin
67,000
36
0.0001
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Difference in PS for various solutes due primarily to pathway available for exchange
<= span style=3D'font-size:88%'>•Plasma membrane
<= span style=3D'font-size:86%'>•largest = area for exchange
•major pa= thway for lipid soluble solutes such as oxygen, carbon dioxide, and urea
<= span style=3D'font-size:88%'>•Small pores
<= span style=3D'font-size:86%'>• 3-4 to 6-7nm in diameter
<= span style=3D'font-size:86%'>•0.02-0.0= 5% of total capillary wall
•major pa= th for small, water soluble solutes such as glucose<= /b>
<= span style=3D'font-size:86%;visibility:hidden'>•
------=_NextPart_01C9C746.4F775AB0 Content-Location: file:///C:/DE4AB113/slides-capillaries_files/slide0060.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" SABS I: Vascular Physiology
SABS I
Capillaries
8
Difference in PS for various solutes due primarily to pathway available for exchange
<= span style=3D'mso-special-format:bullet;color:#99CCFF;mso-color-index:5;positio= n: absolute;left:-7.48%;top:-.08em;font-size:110%'>•Large pores
<= span style=3D'mso-special-format:bullet;color:yellow;position:absolute;left:-6.= 85%; top:-.08em;font-size:110%'>• 30-100= nm in diameter
•theoretically, only one large pore for 300 small pores <= /div>
•major pathway for lipid insoluble substances such as albumin <= /div>
<= span style=3D'font-family:"CG Times";visibility:hidden'>• <= /div>
<= span style=3D'visibility:hidden'>•
------=_NextPart_01C9C746.4F775AB0 Content-Location: file:///C:/DE4AB113/slides-capillaries_files/slide0111.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" SABS I: Vascular Physiology
test
Overview
9
Endothelium Types
=3D15-26
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<= ![if !vml]>
SABS I
Capillaries
10
Difference in PS for same substance between different tissues
Organ
Hydraulic Con= ductivity
Type of Endothel= ium
Brain
3
continuous
Skeletal Muscle
250
continuous
Lung
340
continuous
Heart
860
continuous
Intestinal Mucosa
13,000
fenestrated
Renal Glomerulus
15,000
fenestrated
Liver, spleen
+++
discontinuous
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SABS I
Capillaries
11
III. Capillaries
•<= /span>C.  Water Filtration and Absorption&#= 13;
<= span style=3D'mso-special-format:"numbullet3\,1";color:white;mso-color-index:3; position:absolute;left:-7.32%;top:-.08em;font-size:110%'>1.Importance
•Tissue fluid ÛÞ End Diastolic Volume
•Edema:  can compromise tissue function in= all tissues, tissue perfusion= in encased tissues
•<= /span>
------=_NextPart_01C9C746.4F775AB0 Content-Location: file:///C:/DE4AB113/slides-capillaries_files/slide0112.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" SABS I: Vascular Physiology
test
Overview
12
Severe Malnutrition – Kwashiorkor
3Dkwashiokor
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SABS I
Capillaries
13
III. Capillaries
•<= /span>C.  Water Filtration and Absorption&#= 13;
•2.  <= span style=3D'mso-bidi-font-family:"Times New Roman";color:#99CCFF;mso-color-in= dex: 5'>Filtration/absorption forces
<= span style=3D'mso-special-format:bullet;color:#99CCFF;mso-color-index:5;positio= n: absolute;left:-7.32%;top:-.08em;font-size:110%'>•Hydrostatic pressures = ;
<= span style=3D'color:#99CCFF;mso-color-index:5'>R= 26;capillary pressure (Pc), (15-35 mmHg)
<= span style=3D'color:yellow'>•interstitial= fluid pressure (IF= P or Pt), (~0 mmHg)
<= span style=3D'mso-special-format:bullet;color:#99CCFF;mso-color-index:5;positio= n: absolute;left:-7.32%;top:-.08em;font-size:110%'>•Colloidal osmotic (oncoti= c) pressures
<= span style=3D'color:yellow'>•plasma oncot= ic pressure (pp), (28 mm Hg)
<= span style=3D'color:#99CCFF;mso-color-index:5'>R= 26;tissue oncotic pressure (pt), (3 mmHg) <= /span>
<= span style=3D'visibility:hidden'>1.
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test
Overview
14
Filtration/Absorption Forces
=3D19-19
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Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" SABS I: Vascular Physiology
SABS I
Capillaries
15
III. Capillaries
•<= /span>C.  Water Filtration and Absorption&#= 13;
<= span style=3D'mso-special-format:"numbullet3\,3";color:white;mso-color-index:3; position:absolute;left:-7.32%;top:-.08em;font-size:110%'>3.Changes along an ideal capillary
•Pc decreases from arteriolar to venul= ar end of capillary
<= span style=3D'mso-special-format:bullet;color:yellow;position:absolute;left:-7.= 32%; top:-.08em;font-size:110%'>•Filtration forces decrease
<= span style=3D'mso-special-format:"numbullet3\,4";color:white;mso-color-index:3; position:absolute;left:-7.32%;top:-.08em;font-size:110%'>4.Net exchange <= /span>
<= span style=3D'color:#99CCFF;mso-color-index:5'>R= 26;Filtration forces – Absorption forces
<= span style=3D'mso-special-format:bullet;color:yellow;position:absolute;left:-7.= 32%; top:-.08em;font-size:110%'>•(Pc+ pt) – (pp+P)
------=_NextPart_01C9C746.4F775AB0 Content-Location: file:///C:/DE4AB113/slides-capillaries_files/slide0114.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" SABS I: Vascular Physiology
test
Overview
16
Changes along an ideal capillary
3DJLU-19-19b
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SABS I
Capillaries
17
III. Capillaries
•D.  Sites = of Exchange
D.
•E.  Condit= ions altering transcapillary exchange of H2O = ;
•Hydrostatic pressures:  arteriolar tone, fluid loss, venous compression
•Oncotic pressures:  inflammation, severe malnutrition <= /span>
•Permeability: inflammatio= n
•
------=_NextPart_01C9C746.4F775AB0 Content-Location: file:///C:/DE4AB113/slides-capillaries_files/slide0115.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" SABS I: Vascular Physiology
test
Overview
18
Net Exchange
=3D19-20
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test
Overview
19
Net Absorption
=3D19-20
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SABS I
Capillaries
20
III. Capillaries
CO= NDITION
AL= TERATION
N= ET EFFECT
Arteriolar Vasodilation
­P<= /b>C
Fi= ltration
Hem= orrhage
¯P= C
Ab= sorption
Elevated venous pressure
­P<= /b>C
F= iltration
Ma= lnutrition
¯pp
F= iltration
Congestive heart failure
­P<= /b>C
F= iltration
Ti= ssue inflammation
­P<= /b>C,­PS= , ­pt
F= iltration
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g_scaleHyperlinks=3D(document.all.tags("AREA").length>0) if( g_scaleHyperlinks ) InitHLinkArray() if( g_scaleInFrame||(IsWin("PPTSld") && parent.IsFullScrMode() ) ) document.body.scroll=3D"no" _RSW() if( IsWin("PPTSld") && parent.IsFullScrMode() ) FullScrInit(); =09 MakeSldVis(); ChkAutoAdv() if( runAnimations ) { if( document.all("NSPlay") ) document.all("NSPlay").autoStart =3D false; if( sld.filters && sld.filters.revealtrans ) setTimeout( "document.body.start()", sld.filters.revealtrans.duration * = 1000 ); else document.body.start(); } } function MakeSldVis() { var fTrans=3Dg_showAnimation && SldHasTrans() if( fTrans ) { if( g_bgSound ) { idx=3Dg_bgSound.indexOf(","); pptSound.src=3Dg_bgSound.substr( 0, idx ); pptSound.loop=3D -(parseInt(g_bgSound.substr(idx+1))); } SlideObj.filters.revealtrans.Apply() } SlideObj.style.visibility=3D"visible" if( fTrans ) SlideObj.filters.revealtrans.Play() } function MakeNotesVis() { if( !IsNts() ) return false SlideObj.style.display=3D"none" nObj =3D document.all.item("NotesObj") parent.SetHasNts(0) if( nObj ) { nObj.style.display=3D"" parent.SetHasNts(1) } return 1 } function ChkAutoAdv() { if(SldHasTrans()) SlideObj.onfilterchange=3DAutoAdv else AutoAdv() } function AutoAdv() { if(!IsWin("PPTSld") || !gUseSldTimings )return var sld=3DGetCurSld() if( (sld.mAdvDelay>0) && !parent.IsFramesMode() ) setTimeout("parent.GoToNextSld()",sld.mAdvDelay) } function GetObj(id) { if(g_supportsPPTHTML) return document.all(id); else return document.getElementById(id); } function SldHasTrans() { return SlideObj.style.filter !=3D ""; } function GetSldId() { return sId=3Dlocation.href.substring(location.href.la= stIndexOf('/')+1) } function HideMenu() { if( frames["PPTSld"] && PPTSld.document.all.item("ctx= tmenu") && PPTSld.ctxtmenu.style.display!=3D"none" ) { PPTSld.ctxtmenu.styl= e.display=3D'none'; return true } return false } function IsWin( name ) { return window.name =3D=3D name } function IsNts() { return IsWin("PPTNts") } function IsSldOrNts() { return( IsWin("PPTSld")||IsWin("PPTNts") ) } function SupportsPPTAnimation() { return( navigator.platform =3D=3D "Win32"= && navigator.appVersion.indexOf("Windows")>0 ) } function SupportsPPTHTML() { var appVer=3Dnavigator.appVersion, msie=3DappVer.indexOf("MSIE "), ver=3D0 if( msie >=3D 0 ) ver=3DparseFloat( appVer.substring( msie+5, appVer.indexOf(";",msie) ) ) else ver=3DparseInt(appVer) return( ver >=3D 4 && msie >=3D 0 ) } function _RSW() { if( !g_supportsPPTHTML || IsNts() || ( !g_scaleInFrame && (!IsWin("PPTSld") || !parent.IsFullScrMode()) ) ) return var padding=3D0; if( IsWin("PPTSld") && parent.IsFramesMode() ) padding=3D6 cltWidth=3Ddocument.body.clientWidth-padding cltHeight=3Ddocument.body.clientHeight-padding factor=3D(1.0*cltWidth)/g_origW if( cltHeight < g_origH*factor ) factor=3D(1.0*cltHeight)/g_origH newSize =3D g_origSz * factor if( newSize < 1 ) newSize=3D1 s=3DSlideObj.style s.fontSize=3DnewSize+"px" s.posWidth=3Dg_origW*factor s.posHeight=3Dg_origH*factor s.posLeft=3D(cltWidth-s.posWidth+padding)/2 s.posTop=3D(cltHeight-s.posHeight+padding)/2 if( g_scaleHyperlinks ) ScaleHyperlinks( factor ) } function _InitAnimations() { animRuntimeInstalled =3D ''+document.body.localTime !=3D 'undefined'; isFullScreen =3D (window.name =3D=3D "PPTSld") && !parent.IsFramesMode(); g_animUseRuntime =3D g_showAnimation && animRuntimeInstalled && !(isFullSc= reen && parent.IsSldVisited()); if( g_animUseRuntime ) { collSeq =3D document.all.tags("seq"); if( collSeq !=3D null ) { for(ii=3D0;ii numSlds ) gSldJumpIdx =3D numSlds; if ( gSldJumpIdx >=3D 0 ) { if ( gSldJumpIdx =3D=3D 0 ) gSldJumpIdx =3D 1; var jumpTo =3D parseInt(gSldJumpIdx); gSldJump =3D 0; gSldJumpIdx =3D ""; win.GoToSld( parent.GetSldList().mList[jumpTo-1].mSldHref ) } } } function _KDH() { if( event.keyCode =3D=3D 8 ) { event.returnValue =3D 0; parent.GoToPrevSld(); } } function DocumentOnClick() { if( IsNts() || parent.HideMenu() ) return; if( ( g_allowAdvOnClick 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=3D 0, gHasNarration =3D 0, gOtlOpen =3D true window.gPPTHTML=3DSupportsPPTHTML() var gMainDoc=3Dnew Array(new hrefList("slide0097.htm",1,-1,1),new hrefList(= "slide0055.htm",1,-1,1),new hrefList("slide0056.htm",1,-1,1),new hrefList("= slide0124.htm",1,-1,1),new hrefList("slide0057.htm",1,-1,1),new hrefList("s= lide0058.htm",1,-1,1),new hrefList("slide0059.htm",1,-1,1),new hrefList("sl= ide0060.htm",1,-1,1),new hrefList("slide0111.htm",1,-1,1),new hrefList("sli= de0061.htm",1,-1,1),new hrefList("slide0063.htm",1,-1,1),new hrefList("slid= e0112.htm",1,-1,1),new hrefList("slide0064.htm",1,-1,1),new hrefList("slide= 0113.htm",1,-1,1),new hrefList("slide0065.htm",1,-1,1),new hrefList("slide0= 114.htm",1,-1,1),new hrefList("slide0066.htm",1,-1,1),new hrefList("slide01= 15.htm",1,-1,1),new hrefList("slide0116.htm",1,-1,1),new hrefList("slide006= 7.htm",1,-1,1)); function FullScrInit() { g_allowAdvOnClick =3D GetCurSld().mAdvOnClk document.body.style.backgroundColor=3D"black" document.oncontextmenu=3Dparent._CM; document.onkeydown =3D _KDH; document.ondragstart=3DCancel document.onselectstart=3DCancel self.focus() } function Redirect( frmId ) { var str=3Ddocument.location.hash,idx=3Dstr.indexOf('#'), sId=3DGetSldId() if(idx>=3D0) str=3Dstr.substr(1); if( window.name !=3D frmId && ( sId !=3D str) ) { obj =3D GetObj("Main-File") window.location.href=3Dobj.href+"#"+sId return 1 } return 0 } var MHTMLPrefix =3D CalculateMHTMLPrefix(); function CalculateMHTMLPrefix() { if ( document.location.protocol =3D=3D 'mhtml:') { href=3Dnew String(document.location.href) Start=3Dhref.indexOf('!')+1 End=3Dhref.lastIndexOf('/')+1 if (End < Start) return href.substring(0, Start) else return href.substring(0, End) } return ''; } function GetTags(base,tag) { if(g_supportsPPTHTML) return base.all.tags(tag); else return base.getElementsByTagName(tag); } function UpdNtsPane(){ if(frames["PPTNts"]) PPTNts.location.replace( MHTMLP= refix+GetHrefObj( gCurSld ).mNtsHref ) } function UpdNavPane( sldIndex ){ if(gNavLoaded) PPTNav.UpdNav() } function UpdOtNavPane(){ if(gOtlNavLoaded) PPTOtlNav.UpdOtlNav() } function UpdOtlPane(){ if(gOtlLoaded) PPTOtl.UpdOtl() } function SetHasNts( fVal ) { if( gHasNts !=3D fVal ) { gHasNts=3DfVal UpdNavPane() } } function ToggleOtlText() { gOtlTxtExp=3D!gOtlTxtExp UpdOtlPane() } function ClearMedia() { if (PPTSld.pptSound) PPTSld.pptSound.loop =3D 0; } function FullScreen() { if ( PPTSld.g_animUseRuntime ) PPTSld.document.body.pause(); ClearMedia(); var href =3D ( document.location.protocol =3D=3D 'mhtml:') ? FULLSCR_HREF = : FULLSCR_HREF+"#"+GetHrefObj(gCurSld).mSldHref; if(PPTNav.event.ctrlKey) { var w =3D (window.screen.availWidth * 1.0) / 2.0 var h =3D w * (PPTSld.g_origH * 1.0) / PPTSld.g_origW win =3D window.open( MHTMLPrefix+href,null,"toolbar=3D0,resizable=3D1,top= =3D0,left=3D0," + "width=3D"+ w + ",height=3D" + h ); if( win.document.body && PPTSld.g_animUseRuntime ) win.document.body.PPTSldFrameset=3Dwindow; } else { win =3D window.open( MHTMLPrefix+href,null,"fullscreen=3Dyes" ); if( win.document.body && PPTSld.g_animUseRuntime ) win.document.body.PPTSldFrameset=3Dwindow; } } function ToggleVNarration() { rObj=3DPPTSld.document.all("NSPlay") if( rObj && !PPTSld.g_animUseRuntime ) { if( (rObj.playState =3D=3D 1)||(rObj.playState =3D=3D 0) ) rObj.Play() else if( rObj.playState =3D=3D 2 ) rObj.Pause() else return; } else if( PPTSld.g_animUseRuntime ) { narObj =3D PPTSld.document.all("narrationID") if( narObj ) narObj.togglePause() } } function GetCurSldNum() { obj=3DGetHrefObj(gCurSld) if( obj.mOrigVis =3D=3D 1 ) return obj.mSldIdx else return gCurSld } function GetNumSlds() { if( GetHrefObj(gCurSld).mOrigVis =3D=3D 1 ) return GetSldList().mNumVisSlds; else return GetSldList().mList.length } function GetSldNum( href ) { for(ii=3D0; ii 1 ) PopSldList(); else if( !IsFramesMode() ) { if( gLoopCont ) GoToFirst() else EndShow() } } function GoToPrevSld() { ii=3DgCurSld-1 if( ii > 0 ) { obj=3DGetHrefObj(ii) while ( obj && ( obj.mVis =3D=3D 0 ) && ( ii>0 ) ) obj=3DGetHrefObj(--ii) if( ii =3D=3D 0 ) ii=3D1 GoToSldNum(ii) } } function GoToFirst(){ GoToSld( GetHrefObj(1).mSldHref ) } function GoToLast() { ii=3DGetSldList().mList.length if( ii !=3D gCurSld ) GoToSld( GetHrefObj(ii).mSldHref ) } function GoToSldNum( num ) { if( PPTSld.event ) PPTSld.event.cancelBubble=3Dtrue obj =3D GetHrefObj( num ) obj.mVis=3D1 gPrevSld=3DgCurSld gCurSld =3D num; PPTSld.location.replace(MHTMLPrefix+obj.mSldHref) if( IsFramesMode() ) { UpdNavPane(); UpdOtlPane(); UpdNtsPane() } } function GoToSld( href ) { if( PPTSld.event ) PPTSld.event.cancelBubble=3Dtrue GetHrefObj( GetSldNum(href) ).mVis=3D1 PPTSld.location.replace(MHTMLPrefix+href) } function SldUpdated( id ) { if( id =3D=3D GetHrefObj(gCurSld).mSldHref ) return gPrevSld=3DgCurSld gCurSld=3DGetSldNum(id) if( IsFramesMode() ) { UpdNavPane(); UpdOtlPane(); UpdNtsPane() } } function PrevSldViewed(){ GoToSld( GetHrefObj(gPrevSld).mSldHref ) } function HasPrevSld() { return ( gIsEndShow || ( gCurSld !=3D 1 && GetHrefO= bj( gCurSld-1 ).mVis =3D=3D 1 )||( GetCurSldNum() > 1 ) ) } function HasNextSld() { return (GetCurSldNum() !=3D GetNumSlds()) } function CloseWindow() { if( HideMenu() ) return; var event =3D PPTSld.event; if( !IsFramesMode() && event && (event.keyCode=3D=3D27 || event.keyCode=3D= =3D32 || event.type=3D=3D"click" ) ) window.close( self ); CatchNumKeys( self, event ); } function Unload() { gIsEndShow=3D0; } function SetupEndShow() { gIsEndShow=3D1; PPTSld.document.body.scroll=3D"no"; PPTSld.document.onkeypress=3DCloseWindow; PPTSld.document.onclick=3DCloseWindow; PPTSld.document.oncontextmenu=3D_CM; } function EndShow() { if( IsFramesMode() ) return if( PPTSld.event ) PPTSld.event.cancelBubble=3Dtrue doc=3DPPTSld.document var dir =3D doc.body.dir if( dir !=3D "rtl" ) dir =3D "ltr"; doc.open() doc.writeln('


' + ENDSHOW_MESG + '

') doc.close() } function SetSldVisited(){ GetSldList().mList[gCurSld-1].mVisited=3Dtrue } function IsSldVisited(){ return GetSldList().mList[gCurSld-1].mVisited } function hrefList( sldHref, visible, advDelay, advClk ) { this.mSldHref=3D this.mNtsHref =3D sldHref this.mOrigVis=3D this.mVis =3D visible this.mVisited=3D false this.mAdvDelay=3D advDelay this.mAdvOnClk=3D advClk } function SldList(arr,curSld,fEnd) { this.mCurSld =3D curSld; this.mList =3D new Array(); var idx =3D 1; for(ii=3D0;ii 0) { PushSldList(sldList,fEnd); gCurSld =3D 1; } else if( PPTSld.event ) PPTSld.event.cancelBubble=3Dtrue } function PushSldList(arr,fEnd) { var ii =3D gSldStack.length; gSldStack[ii] =3D new SldList(arr,gCurSld,fEnd); GoToSld( gSldStack[ii].mList[0].mSldHref ); } function PopSldList() { if (gSldStack[gSldStack.length-1].fEndShow) EndShow() else { gCurSld =3D gSldStack[gSldStack.length-1].mCurSld; gSldStack[gSldStack.length-1] =3D null; gSldStack.length--; var sldList =3D gSldStack[gSldStack.length-1]; GoToSld( sldList.mList[gCurSld - 1].mSldHref ); } } var custShowList=3Dnew Array(); function ImgBtn( oId,bId,w,action ) { var t=3Dthis t.Perform =3D _IBP t.SetActive =3D _IBSetA t.SetInactive=3D _IBSetI t.SetPressed =3D _IBSetP t.SetDisabled=3D _IBSetD t.Enabled =3D _IBSetE t.ChangeIcon =3D null t.UserAction =3D action t.ChgState =3D _IBUI t.mObjId =3D oId t.mBorderId=3D bId t.mWidth =3D w t.mIsOn =3D t.mCurState =3D 0 } function _IBSetA() { if( this.mIsOn ) { obj=3Dthis.ChgState( gHiliteClr,gShadowClr,2 ) obj.style.posTop=3D0 } } function _IBSetI() { if( this.mIsOn ) { obj=3Dthis.ChgState( gFaceClr,gFaceClr,1 ) obj.style.posTop=3D0 } } function _IBSetP() { if( this.mIsOn ) { obj=3Dthis.ChgState( gShadowClr,gHiliteClr,2 ) obj.style.posLeft+=3D1; obj.style.posTop+=3D1 } } function _IBSetD() { obj=3Dthis.ChgState( gFaceClr,gFaceClr,0 ) obj.style.posTop=3D0 } function _IBSetE( state ) { var t=3Dthis GetObj( t.mBorderId ).style.visibility=3D"visible" if( state !=3D t.mIsOn ) { t.mIsOn=3Dstate if( state ) t.SetInactive() else t.SetDisabled() } } function _IBP() { var t=3Dthis if( t.mIsOn ) { if( t.UserAction !=3D null ) t.UserAction() if( t.ChangeIcon ) { obj=3DGetObj(t.mObjId) if( t.ChangeIcon() ) obj.style.posLeft=3Dobj.style.posLeft+(t.mCurState-4)*t.mWidth else obj.style.posLeft=3Dobj.style.posLeft+(t.mCurState-0)*t.mWidth } t.SetActive() } } function _IBUI( clr1,clr2,nextState ) { var t=3Dthis SetBorder( GetObj( t.mBorderId ),clr1,clr2 ) obj=3DGetObj( t.mObjId ) obj.style.posLeft=3Dobj.style.posLeft+(t.mCurState-nextState)*t.mWidth-obj= .style.posTop t.mCurState=3DnextState return obj } function TxtBtn( oId,oeId,action,chkState ) { var t=3Dthis t.Perform =3D _TBP t.SetActive =3D _TBSetA t.SetInactive=3D _TBSetI t.SetPressed =3D _TBSetP t.SetDisabled=3D _TBSetD t.SetEnabled =3D _TBSetE t.GetState =3D chkState t.UserAction =3D action t.ChgState =3D _TBUI t.mObjId =3D oId t.m_elementsId=3D oeId t.mIsOn =3D 1 } function _TBSetA() { var t=3Dthis if( t.mIsOn && !t.GetState() ) t.ChgState( gHiliteClr,gShadowClr,0,0 ) } function _TBSetI() { var t=3Dthis if( t.mIsOn && !t.GetState() ) t.ChgState( gFaceClr,gFaceClr,0,0 ) } function _TBSetP() { if( this.mIsOn ) this.ChgState( gShadowClr,gHiliteClr,1,1 ) } function _TBSetD() { this.ChgState( gFaceClr,gFaceClr,0,0 ) this.mIsOn =3D 0 } function _TBSetE() { var t=3Dthis if( !t.GetState() ) t.ChgState( gFaceClr,gFaceClr,0,0 ) else t.ChgState( gShadowClr,gHiliteClr,1,1 ) t.mIsOn =3D 1 } function _TBP() { var t=3Dthis if( t.mIsOn ) { if( t.UserAction !=3D null ) t.UserAction() if( !t.GetState ) return if( t.GetState() ) t.SetPressed() else t.SetActive() } } function _TBUI( clr1,clr2,lOffset,tOffset ) { SetBorder( GetObj( this.mObjId ),clr1,clr2 ) Offset( GetObj( this.m_elementsId ),lOffset,tOffset ) } function Offset( obj, top, left ){ obj.style.top=3Dtop; obj.style.left=3Dle= ft } function SetBorder( obj, upperLeft, lowerRight ) { s=3Dobj.style; s.borderStyle =3D "solid" s.borderWidth =3D 1 s.borderLeftColor =3D s.borderTopColor =3D upperLeft s.borderBottomColor=3D s.borderRightColor =3D lowerRight } function GetBtnObj(){ return gBtnArr[window.event.srcElement.id] } function BtnOnOver(){ b=3DGetBtnObj(); if( b !=3D null ) b.SetActive() } function BtnOnDown(){ b=3DGetBtnObj(); if( b !=3D null ) b.SetPressed() } function BtnOnOut(){ b=3DGetBtnObj(); if( b !=3D null ) b.SetInactive() } function BtnOnUp() { b=3DGetBtnObj() if( b !=3D null ) b.Perform() else Upd() } function GetNtsState(){ return parent.gNtsOpen } function GetOtlState(){ return parent.gOtlOpen } function GetOtlTxtState(){ return parent.gOtlTxtExp } function NtsBtnSetFlag( fVal ) { s=3Ddocument.all.item( this.m_flagId ).style s.display=3D"none" if( fVal ) s.display=3D"" else s.display=3D"none" } function _BSetA_Border(){ b =3D gBtnArr[this.mObjId]; if( b !=3D null ) b.S= etActive() } function _BSetI_Border(){ b =3D gBtnArr[this.mObjId]; if( b !=3D null ) b.S= etInactive() } function _BSetP_Border(){ b =3D gBtnArr[this.mObjId]; if( b !=3D null ) b.S= etPressed() } function _BSetA_BorderImg() { b =3D gBtnArr[this.mBorderId] if( b !=3D null && this.mIsOn && !b.GetState() ) { obj=3Dthis.ChgState( gHiliteClr,gShadowClr,2 ) obj.style.posTop=3D0 } } function _BSetI_BorderImg() { b =3D gBtnArr[this.mBorderId] if( b !=3D null && this.mIsOn && !b.GetState() ) { obj=3Dthis.ChgState( gFaceClr,gFaceClr,1 ) obj.style.posTop=3D0 } } var gHiliteClr=3D"THREEDHIGHLIGHT",gShadowClr=3D"THREEDSHADOW",gFaceClr=3D"= THREEDFACE" var gBtnArr =3D new Array() gBtnArr["nb_otl"] =3D new TxtBtn( "nb_otl","nb_otlElem",parent.ToggleOtlPan= e,GetOtlState ) gBtnArr["nb_otlElem"] =3D new TxtBtn( "nb_otl","nb_otlElem",parent.ToggleOt= lPane,GetOtlState ) gBtnArr["nb_nts"] =3D new ImgBtn( "nb_nts","nb_ntsBorder",10,parent.ToggleN= tsPane ) gBtnArr["nb_nts"].SetActive =3D _BSetA_BorderImg; gBtnArr["nb_nts"].SetInactive =3D _BSetI_BorderImg; gBtnArr["nb_ntsBorder"] =3D new TxtBtn( "nb_ntsBorder","nb_ntsElem",parent.= ToggleNtsPane,GetNtsState ) gBtnArr["nb_ntsElem"] =3D new TxtBtn( "nb_ntsBorder","nb_ntsElem",parent.To= ggleNtsPane,GetNtsState ) gBtnArr["nb_prevBorder"] =3D gBtnArr["nb_prev"]=3D new ImgBtn( "nb_prev","n= b_prevBorder",30,parent.GoToPrevSld ) gBtnArr["nb_nextBorder"] =3D gBtnArr["nb_next"]=3D new ImgBtn( "nb_next","n= b_nextBorder",30,parent.GoToNextSld ) gBtnArr["nb_sldshw"]=3D new ImgBtn( "nb_sldshw","nb_sldshwBorder",18,parent= .FullScreen ) gBtnArr["nb_sldshwBorder"] =3D new TxtBtn( "nb_sldshw","nb_sldshwBorder",pa= rent.FullScreen,null ) gBtnArr["nb_sldshwBorder"].SetActive =3D _BSetA_Border; gBtnArr["nb_sldshwBorder"].SetInactive =3D _BSetI_Border; gBtnArr["nb_sldshwText"] =3D new TxtBtn( "nb_sldshw","nb_sldshwText",parent= .FullScreen,null ) gBtnArr["nb_sldshwText"].SetActive =3D _BSetA_Border; gBtnArr["nb_sldshwText"].SetInactive =3D _BSetI_Border; gBtnArr["nb_voice"] =3D gBtnArr["nb_voiceBorder"] =3D new ImgBtn( "nb_voice= ","nb_voiceBorder",18,parent.ToggleVNarration ) gBtnArr["nb_otlTxtBorder"] =3D gBtnArr["nb_otlTxt"]=3D new ImgBtn( "nb_otlT= xt","nb_otlTxtBorder",23,parent.ToggleOtlText ) gBtnArr["nb_ntsBorder"].m_flagId=3D "nb_nts" gBtnArr["nb_ntsBorder"].SetFlag =3D NtsBtnSetFlag gBtnArr["nb_otlTxt"].ChangeIcon=3D GetOtlTxtState var sNext=3D"Next",sPrev=3D"Previous",sEnd=3D"End Show",sFont=3D"Arial",sAr= row=3D"Arrow",sFreeform=3D"Freeform",sRect=3D"Rectangle",sOval=3D"Oval" function ShowMenu() { BuildMenu(); var doc=3DPPTSld.document.body,x=3DPPTSld.event.clientX+doc.scrollLeft,y= =3DPPTSld.event.clientY+doc.scrollTop m =3D PPTSld.document.all.item("ctxtmenu") m.style.pixelLeft=3Dx if( (x+m.scrollWidth > doc.clientWidth)&&(x-m.scrollWidth > 0) ) m.style.pixelLeft=3Dx-m.scrollWidth m.style.pixelTop=3Dy if( (y+m.scrollHeight > doc.clientHeight)&&(y-m.scrollHeight > 0) ) m.style.pixelTop=3Dy-m.scrollHeight m.style.display=3D"" } function _CM() { if( !parent.IsFullScrMode() ) return; if(!PPTSld.event.ctrlKey) { ShowMenu() return false } else HideMenu() } function BuildMenu() { if( PPTSld.document.all.item("ctxtmenu") ) return var mObj=3DCreateItem( PPTSld.document.body ) mObj.id=3D"ctxtmenu" mObj.style.visibility=3D"hidden" var s=3DmObj.style s.position=3D"absolute" s.cursor=3D"default" s.width=3D"120px" SetCMBorder(mObj,"menu","black") var iObj=3DCreateItem( mObj ) SetCMBorder( iObj, "threedhighlight","threedshadow" ) iObj.style.padding=3D2 CreateMenuItem( iObj,sNext,M_GoNextSld,M_True ) CreateMenuItem( iObj,sPrev,M_GoPrevSld,M_HasPrevSld ) CreateSeparator( iObj ) CreateMenuItem( iObj,sEnd,M_End,M_True ) mObj.style.visibility=3D"visible" } function Cancel() { window.event.cancelBubble=3Dtrue; window.event.returnVa= lue=3Dfalse } function Highlight() { ChangeClr("activecaption","threedhighlight") } function Deselect() { ChangeClr("threedface","menutext") } function Perform() { e=3DPPTSld.event.srcElement if( e.type=3D=3D"menuitem" && e.IsActive() ) e.Action() else PPTSld.event.cancelBubble=3Dtrue } function ChangeClr( bg,clr ) { e=3DPPTSld.event.srcElement if( e.type=3D=3D"menuitem" && e.IsActive() ) { e.style.backgroundColor=3Dbg e.style.color=3Dclr } } function M_HasPrevSld() { return( parent.HasPrevSld() ) } function M_GoNextSld() { if( gIsEndShow ) M_End(); 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charset="us-ascii" SABS I: Vascular Physiology ------=_NextPart_01C9C746.4F775AB0 Content-Location: file:///C:/DE4AB113/slides-capillaries_files/outline.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii"
 No= tes
Slide Show
Outline
= = = = = =
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